MOTS-C — 40mg
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a mitochondrial-derived peptide encoded within the mitochondrial genome. It is an active area of research in mitochondrial biology, exercise physiology, and metabolic science.
Satisfaction Guarantee: If your order arrives damaged or does not match the certified specification, we will replace it. No questions asked.
Specifications
- Sequence
- 16-amino acid mitochondrial-derived peptide
- Molecular Weight
- 2,174.45 Da
- Quantity
- 40mg per vial
- Purity
- ≥98% (HPLC verified)
- Form
- Lyophilized powder
- Appearance
- White powder
- Storage
- -20°C recommended
Certificate of Analysis
This product is supplied with a third-party certificate of analysis verifying ≥98% purity via HPLC.
Download COA (PDF)Research Applications
MOTS-C was first identified by Dr. Changhan David Lee at USC in 2015 as a mitochondrial-derived signaling peptide. Published research has investigated its role in AMPK pathway activation, glucose metabolism regulation, and exercise-mimetic effects. Preclinical models have demonstrated its activity in fatty acid oxidation, insulin sensitivity pathways, and metabolic homeostasis. One small-scale human study (CB4211 analog) has been conducted, with broader human research still limited.
Key Published Research
- Lee et al., Cell Metabolism 2015 — Discovery and initial characterization
- Reynolds et al., Cell Metabolism 2021 — Exercise-induced MOTS-C translocation
Storage & Handling
Store lyophilized powder at -20°C. Protect from light and moisture. Once reconstituted, store at 2-8°C and use within 21 days.
